黄守杰

发布时间:2011-08-18         浏览次数:2428


黄守杰(Shou-Jie Huang)

高级实验师

硕士生导师

Tel: 0592-2188393(O)

E-mail: huangshoujie@xmu.edu.cn

学习经历:

2008获厦门大学生物化学与分子生物学硕士学位

1999获北京大学公共卫生学院医学学士学位

工作经历:

2012厦门大学公共卫生学院高级实验师

2011厦门大学公共卫生学院实验师

2004厦门大学医学院实验师

1999厦门大学医学院助理实验师

个人简介:

 中国民主同盟会会员,中华医学会会员。2006年至今主要从事疫苗临床试验和现场流行病学研究,在疫苗临床试验具有丰富的经验。作为主要研究成员完成国家一类新药戊型肝炎疫苗Ⅲ期临床试验,该疫苗现已获得新药证书和生产文号,成为世界上第一个成功上市的戊肝疫苗。作为主要研究人员主持或参与国家自然科学基金、国家传染病重大科技专项、国家863项目等多个项目。已发表论文20篇,其中SCI论文13篇。

代表性论文:

1. Shu Chen, Zi Zhou, Fei-Xue Wei, Shou-Jie Huang, Zhong Tan, Ya Fang, Feng-Cai Zhu, Ting Wu,Jun Zhang, Ning-Shao Xia. Modeling the long-term antibody response of ahepatitis E vaccine [J]. Vaccine, 2015. (IF:3.624)

2. Ting Wu, Yue-Mei Hu, Juan Li, Kai Chu, Shou-Jie Huang, Hui Zhao, Zhong-Ze Wang, Chang-Lin Yang, Han-MinJiang, Yi-Jun Wang, Zhi-Jie Lin, Hui-Rong Pan, Wei Sheng, Fei-Xue Wei, Shao-WeiLi, Ying Wang, Feng-Cai Zhu, Chang-Gui Li, Jun Zhang, Ning-Shao Xia.Immunogenicity and safety of an E. coli–produced bivalent human papillomavirus(type 16 and 18) vaccine: a randomized controlled phase 2 clinical trial [J]. Vaccine,2015, 33: 3940-3946. (IF:3.624)

3. Jun Zhang, Xue-Feng Zhang, Shou-Jie Huang, Ting Wu, Yue-Mei Hu, Zhong-Ze Wang, HuaWang, Han-Min Jiang, Yi-Jun Wang, Qiang Yan, Meng Guo, Xiao-Hui Liu, Jing-XinLi, Chang-Lin Yang, Quan Tang, Ren-Jie Jiang, Hui-Rong Pan, Yi-Min Li, J.Wai-Kuo Shih, Mun-Hon Ng, Feng-Cai Zhu, Ning-Shao Xia. Long-term efficacy of ahepatitis E vaccine [J]. New England Journal of Medicine,2015, 372(10): 914-922. (IF: 55.873)

4. Shou-Jie Huang, Xiao-Hui Liu, Jun Zhang,Mun-Hon Ng. Protective immunity against HEV [J]. Current opinion in virology,2014, 5: 1-6. (IF: 6.298)

5. Feng-Cai Zhu, Shou-JieHuang, Ting Wu, Xue-Feng Zhang, Zhong-Ze Wang, Xing Ai, Qiang Yan, Chang-LinYang, Jia-Ping Cai, Han-Min Jiang, Yi-Jun Wang, Mun-Hon Ng, Jun Zhang, Ning-ShaoXia. Epidemiology of Zoonotic Hepatitis E: A Community-Based Surveillance Studyin a Rural Population in China [J]. PloS one, 2014, 9(1): e87154. (IF: 3.234,Co-First Author)

6. Hui Zhao, Zhi-Jie Lin, Shou-JieHuang, Juan Li, Xiao-Hui Liu, Meng Guo, Jun Zhang, Ning-Shao Xia,Hui-Rong Pan, Ting Wu, Chang-Gui Li. Correlation between ELISA andpseudovirion-based neutralisation assay for detecting antibodies against humanpapillomavirus acquired by natural infection or by vaccination [J]. HumanVaccines &Immunotherapeutics, 2014, 10(3): 740-746. (IF: 2.366)

7. Yuemei Hu, Shou-JieHuang, Kai Chu, Ting Wu, Zhong-Ze Wang, Chang-Lin Yang, Jia-Ping Cai,Han-Min Jiang, Yi-Jun Wang, Meng Guo, Xiao-Hui Liu, Hong-Jiang Huang, Feng-CaiZhu, Jun Zhang, Ning-Shao Xia. Safety of an Escherichia coli-expressed bivalenthuman papillomavirus (types 16 and 18) L1 virus-like particle vaccine: Anopen-label phase I clinical trial [J]. Human vaccines & immunotherapeutics,2014, 10(2): 469-475. (IF: 2.366, Co-FirstAuthor)

8. J. Zhang, X.-F. Zhang, C. Zhou, Z.-Z. Wang, S.-J. Huang, X. Yao, Z.-L. Liang,T. Wu, J.-X. Li, Q. Yan, C.-L. Yang, H.-M. Jiang, H.-J. Huang, Y.-L. Xian, J.W.-K. Shih, M.-H. Ng, Y.-M. Li, J.-Z. Wang, F.-C. Zhu, N.-S. Xia. Protectionagainst hepatitis E virus infection by naturally acquired and vaccine-inducedimmunity [J]. Clinical Microbiology and Infection, 2014, 20(6): O397-O405.(IF: 5.768)

9. Ting Wu, Shou-JieHuang, Feng-Cai Zhu, Xue-Feng Zhang, Xing Ai, Qiang Yan, Zhong-Ze Wang,Chang-Lin Yang, Han-Min Jiang, Xiao-Hui Liu, Meng Guo, Hai-Lian Du, Mun-Hon Ng,Jun Zhang, Ningshao Xia. Immunogenicity and safety of hepatitis E vaccine inhealthy hepatitis B surface antigen positive adults [J]. Human Vaccines &Immunotherapeutics, 2013, 9(11): 2474-2479. (IF: 2.131)

10. Ting Wu, Feng-Cai Zhu, Shou-JieHuang, Xue-Feng Zhang, Zhong-Ze Wang, Jun Zhang, Ning-Shao Xia. Safetyof hepatitis E vaccine for pregnant women: a preliminary analysis [J]. Hepatology,2012, 55(6): 2038-2038. (IF: 12.003)

11. Shoujie Huang, Xuefeng Zhang, HanminJiang, Qiang Yan, Xing Ai, Yijun Wang, Jiaping Cai, Lang Jiang, Ting Wu, ZhongzeWang, Li Guan, J. Wai Kuo Shih, Mun-Hon Ng, Fengcai Zhu, Jun Zhang, NingshaoXia. Profile of acute infectious markers in sporadic hepatitis E[J].PloSone, 2010, 5(10): e13560. (IF:4.411, Co-First Author)

12. Feng-Cai Zhu, Jun Zhang, Xue-Feng Zhang, Cheng Zhou, Zhong-ZeWang, Shou-Jie Huang, HuaWang, Chang-Lin Yang, Han-Min Jiang, Jia-Ping Cai, Yi-Jun Wang, Xing Ai,Yue-Mei Hu, Quan Tang, Xin Yao, Qiang Yan, Yang-Ling Xian, Ting Wu, Yi-Min Li, JiMiao, Mun-Hon Ng, James Wai-Kuo Shih, Ning-Shao Xia. Efficacy and safety of arecombinant hepatitis E vaccine in healthy adults: a large-scale, randomised,double-blind placebo-controlled, phase 3 trial [J]. The Lancet, 2010,376(9744): 895-902. (IF:33.633)

项目:

1. 主持一项国家自然科学基金项目(课题编号:81373061);参与1863项目(课题编号:2006AA02A209),1项国家科技重大专项课题(课题编号:2012ZX09101316);

2. 做为主要研究成员完成国家一类新药重组戊型肝炎疫苗(大肠杆菌)Ⅲ期临床试验,该疫苗现已获得新药证书和生产文号,成为世界上第一个成功上市的戊肝疫苗;

3. 做为主要研究成员完成重组HPV1618双价疫苗(大肠杆菌)Ⅰ、Ⅱ期临床试验;

4. 做为主要研究成员参与重组HPV1618双价疫苗(大肠杆菌)Ⅲ期临床试验;

5. 做为主要研究成员参与重组(大肠杆菌)HPV611双价疫苗Ⅰ期临床试验。

获奖:

1. 2014年获得厦门大学校庆中国银行教科辅奖教金;

2. 2012年获得厦门大学公共卫生学院养生堂奖教金;

3. 2012年获得江苏省科学技术奖一等奖(排名:9);

4. 2011年获得戊肝疫苗新药证书和生产文号(国药证字S20110005)。