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Rui Tian

Rui Tian Associate Professor

Position:

Email: rtian@xmu.edu.cn

Office:

Research Area: Development of near-infrared two-region fluorescent imaging probes and their bioimaging applications; development of a diagnostic system based on albumin and its variants.

Representative Publications(# co-first author, * Corresponding author)

1. Feng, X#; Wei, L#; Liu, Y#; Chen, X*; Tian, R*. Orchestrated Strategies for Developing Fluorophores for NIR‐II Imaging. Adv. Healthcare Mater. 2023, 2300537.

2. Tian, R*; Feng, X; Wei, L; Dai, D; Ma, Y; Pan, H; Ge S; Bai, L; Ke, C; Liu, Y; Lang, L; Zhu, S*; Sun, H; Yu, Y*; Chen, X*. A genetic engineering strategy for editing near-infrared-II fluorophores. Nat. Commun. 2022, 13, 2853.

3. Tian, R#; Zeng, Q#; Zhu, S*; Lau, J; Chandra, S; Hu, Z; Niu, G; Kiesewetter, D; Sun, H*; Zhang, X; Antaris, AL; Brooks, BR; Chen, X*. Albumin chaperoned cyanine dye yields super bright NIR-II fluorophore with enhanced pharmacokinetics. Sci. Adv. 2019, 5, eaaw0672.

4. Bai, L; Hu Z; Han T; Wang Y; Xu J; Jiang G; Feng X; Sun B; Liu X; Tian, R*; Sun, H; Zhang S; Chen, X*; Zhu, S*. Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging. Theranostics, 2022, 12, 4536.

5. Wang, S; Tian, R*; Zhang, X; Cheng, G; Yu, P; Chang, J*; Chen, X*. Beyond Photo: Xdynamic Therapies in Fighting Cancer. Adv. Mater. 2021, 33, 2007488.

6. Meng, Q#; Tian, R#; Long, H; Wu, X; Lai, J; Zharkova, O; Wang, J; Chen, X; Rao, L. Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm. Adv. Mater. 2021, 33, 2100012.

7. Tian, R*; Ke, C; Rao, L; Lau, J; Chen, X*. Multimodal stratified imaging of nanovaccines in lymph nodes for improving cancer immunotherapy. Adv. Drug Deliver. Rev. 2020, 161-162, 145-160.

8. Tian, R#; Ma, H #; Zhu, S*; Lau, J; Ma, R; Liu, Y; Lin, L; Chandra, S; Wang, S; Niu ,G; Zhang, M*; Antaris, A; Hettie, K; Yang, B; Liang, Y*; Chen, X*. Multiplexed NIR-II imaging for lymph node-invaded cancer detection and full-process light exposure surgery. Adv. Mater., 2020, 32, 1907365. (Back cover)

9. Tian, R; Shen, Z; Zhou, Z; Munasinghe, J; Zhang, X; Jacobson, O; Zhang, M; Niu, G; Pang, D; Cui, R*; Zhu, S*; Chen, X*. Ultrasmall Quantum Dots with Broad‐Spectrum Metal Doping Ability for Trimodal Molecular Imaging. Adv. Funct. Mater., 2019, 26, 1901671. 14.136.

10. Tian, R; Zhu, S*; Zeng, Q; Lang, L; Ma, Y; Kiesewetter, D; Liu, Y; Fu, X; Lau, J; Zhu, G; Jacobson, O; Wang, Z; Dai, Y; Yu, G; Brooks, B; Liu, G; Niu, G*; Chen, X*. An albumin sandwich enhances in vivo circulation and stability of metabolically labile peptides. Bioconjugate Chem. 2019, 30, 1711-1723.

11. Tian, R#; Ma, H#; Yang, Q#; Wan, H#; Zhu, S*; Chandra, S; Sun, H*; Kiesewetter, D; Niu, G; Liang, Y;Chen, X*. Rational design of a super-contrast NIR-II fluorophore affords high-performance NIR-II molecular imaging guided microsurgery. Chem. Sci. 2019, 10, 326-332.

12. Tian, R; Jacobson, O*; Niu, G; Kiesewetter, D; Wang, Z; Zhu, G; Ma, Y; Liu, G; Chen, X*. Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy. Theranostics. 2018, 8, 735-745.

13. Zhou, Z#; Tian, R#; Wang, Z; Yang, Z; Liu, Y; Liu, G; Wang, R; Gao, J; Song, J; Nie, L*; Chen, X*. Artificial local magnetic field inhomogeneity enhances T2 relaxivity. Nat. Commun. 2017, 8, 15468.

14. Zhu, S#; Hu, Z#; Tian, R#; Yung, B; Yang, Q; Zhao, S; Kiesewetter, D; Niu, G; Sun, H; Antaris, A; Chen, X. Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging. Adv. Mater. 2018, 30, 1802546.

15. Yang, Z#; Tian, R#; Wu, J; Fan, Q*; Yung, B; Niu, G; Jacobson, O; Wang, Z; Liu, G*; Yu, G; Huang, W; Song, J*; Chen, X*. Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging. ACS Nano. 2017, 11, 4247-4255.

16. Zhu, S; Tian, R; Antaris, A; Chen, X*; Dai, H*.Near-Infrared-II molecular dyes for cancer imaging and surgery. Adv. Mater. 2019, 31, 201900321.