微信

简体中文
 
 

Faculty

Qixu Cai

Qixu Cai Associate Professor

Position:

Email: qxcai@xmu.edu.cn

Office:

Research Area:

Selected Publications (#: Co-author)

1. Cai, Q., Zeng, M., Wu, X., Wu, H., Zhan, Y., Tian, R., and Zhang, M. (2021) CaMKIIα-driven, phosphatase-checked postsynaptic plasticity via phase separation. Cell Res 31: 37-51.

2. Wu, X.#, Cai, Q.#, Shen, Z., Chen, X., Zeng, M., Du, S. and Zhang, M. (2019) RIM and RIM-BP form presynaptic active-zone-like condensates via phase separation. Mol Cell 73 (5): 871-984.

3. Cai, Q., Hosokawa, T., Zeng, M., Hayashi, Y. and Zhang, M. (2020) Shank3 binds to and stabilizes the active form of Rap1 and HRas GTPases via its NTD-ANK tandem with distinct mechanisms. Structure 28 (3): 290-300.

4. Wu, X.#, Cai, Q.#, Chen, Y., Zhu, S., Mi, J., Wang, J. and Zhang, M. (2020) Structural basis for the high-affinity interaction between CASK and Mint1. Structure 28 (6): 664-673.

5. Geng, Y.#, Liu, C.#, Cai, Q.#, Luo, Z., Miao, H., Shi, X., Xu, N., Fung, C.P., Choy, T.T., Yan, B., Li, N., Qian, P., Zhou, B., Zhu, G. (2021) Crystal structure of parallel G-quadruplex formed by the two-repeat ALS and FTD related GGGGCC sequence. Nucleic Acids Res 49 (10): 5881-5890.

6. Cai, Q.#, Yameen, M.#, Liu, W.#, Gao, Z., Li, Y., Peng, X., Cai, Y., Wu, C., Zheng, Q., Li, J. and Lin, T. (2013) Conformational plasticity of the 2A proteinase from enterovirus 71. J Virol 87: 7348-7356.

7. Wu, C.#, Cai, Q.#, Chen, C.#, Li, N., Peng, X., Cai, Y., Yin, K., Chen, X., Wang, X., Zhang, R., Liu, L., Chen, S., Li, J. and Lin, T. (2013) Structures of enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir. Acta Crystallogr D Biol Crystallogr 69: 866-871.

8. Zhang, L.#, Huang, G.#, Cai, Q.#, Zhao, C., Tang, L., Ren, H., Li, P., Li, N., Huang, J., Chen, X., Guan, Y., You, H., Chen, S., Li, J., Lin, T. (2016) Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71. J Mol Recognit 29: 520-527.

9. Wu, C.#, Zhang, L.#, Li, P.#, Cai, Q.#, Peng, X., Yin, K., Chen, X., Ren, H., Zhong, S., Weng, Y., Guan, Y., Chen, S., Wu, J., Li, J., Lin, T. (2016) Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71. BBA-Gen Subjects 1860: 1299-1307.